SIIM-CAIMI
Conference on Artificial Intelligence in Medical Imaging
Oct 26-27, 2026
University of Pennsylvania, Philadelphia, PA
Hip vs Hype: Research Frontiers in Agentic AI and Foundation Models
Agentic AI systems and foundation models are rapidly becoming central to the future of medical AI research, with proposed applications across imaging, reporting, clinical decision support, workflow orchestration, patient communication, and real-world deployment. Yet the field is still early, and many claims remain difficult to evaluate. Performance may depend on benchmark design, data leakage, prompt sensitivity, model access, evaluation strategy, clinical context, and the degree of human oversight.
This interactive CAIMI research session will use a “Hip vs Hype” format to critically examine emerging directions in agentic AI and foundation models. Rather than focusing only on what is new or exciting, the discussion will ask what evidence is needed to determine whether these approaches represent meaningful scientific progress, translational opportunity, or premature enthusiasm.
Using polls, participants will vote on key topics in agentic AI and foundation models, including autonomous clinical agents, multi-agent workflows, AI-assisted reporting, patient-facing systems, model evaluation, safety monitoring, and governance. Each poll will be followed by brief commentary and audience discussion focused on research gaps, methodological limitations, clinical relevance, and opportunities for collaborative study.
The goal of the session is to create a dynamic, audience-driven conversation that helps researchers distinguish promising frontiers from under-validated claims and identify rigorous research questions for the next phase of medical AI.
Objectives
Critically evaluate emerging applications of agentic AI and foundation models in medicine using research-focused evidence standards.
Identify methodological limitations in current studies, including benchmark contamination, lack of external validation, prompt sensitivity, limited clinical endpoints, and insufficient prospective evaluation.
Describe how agentic AI introduces new research questions around autonomy, orchestration, reliability, human oversight, accountability, and safety.
Discuss the opportunities and limitations of foundation models for imaging, reporting, multimodal reasoning, patient communication, and clinical workflow support.
Speakers
Katherine P. Andriole, PhD, FSIIM
Associate Dean for Health AI Strategy & Innovation, UCLA David Geffen School of Medicine
Director, UCLA Center for AI and SMART Health
Tessa Cook, MD, PhD, CIIP, FSIIM
Associate Professor of Radiology, Vice Chair of Informatics
Perelman School of Medicine at the University of Pennsylvania
Dania Daye, MD, PhD
Vice Chair of Practice Transformation, Director of the Center for High Value Imaging (CHVI), Associate Professor of Interventional Radiology
University of Wisconsin School of Medicine and Public Health
Satvik Tripathi
Doctoral Student, Researcher in the Department of Radiology & Radiation Oncology
Fellow, Penn Center for Cancer Care Innovation
SESSION ID
1004
DATE
MON, OCT 26
TIME
1:00 PM – 1:45 PM ET
LOCATION
Smilow Rubenstein Auditorium
CONTINUING EDUCATION
ASRT-RT | CAMPEP-MPCEC | SIIM IIP-CIIP